Note on Trump

Trump is the worlds greatest WHINER. He makes himself the victim every time he opens his mouth. He makes America the victim of other countries. The American People the victim of other peoples. He is wrong. We are far better off than others and working hard to make their lives better too.We have shown the world equality at work can lead to poorly educated, over forceful, self-centered people can become billionaires.

Gypsies, Trumps,  and thieves.

Trump has flip-flopped so many times the pancake is a ball.

Rejuvenation and longevity

In 1989 I started by delusional thinking. Very long life is thermodynamically possible, probable, and therefore inevitable.
If the nominal chemical content of the various cells of the 25 year old body are maintained then the whole body will work as the 25 year old body works. Molecular content can be kept nominal by adding energy to the cellular process that will maintain the nominal concentrations of the thousand or so molecules of each of the 20 to 40 or so types of cells in the body. The concept is simple and clean and rests on the second law: you can do what you want in a chemical system if you pay the energy and matter price to do it. The 25 year old body does it so it can be done. But it isn't easy.
De Grey's method looks attractive because it points to why the molecular nominal concentrations fall below nominal, garbage collection fails to keep up. Help it keep up an you get closer to nominal.
But the De Pinho and Sahan telermerase experiments show that you can keep things near to nominal by keeping the cells from stepping on themselves by unwinding the chromosomes and having genes corrupted.
The stem cell research shows that if we can keep them working their daughter cells will be closer to nominal than aged cells concentrations are.
Parabiosis has shown that the young body produces molecules that keep the bodies various cell types with nominal concentrations. The Harvard group under Amy Wagers, and other groups, says gdf11 and other protein concentrations fall off in the body as it ages and papabiosis pushes the concentrations back toward nominal in the old body with the greater concentration from the young. More than other procedures this tends to support the idea that nominal cell molecular concentrations for each of the various cell types is something that bio-engineering can accomplish.
Rejuvenation and longevity are an information problem: the nominal concentrations need to be documented, their maintenance needs to be understood, and natures failure to maintain them needs to be corrected. The young body does it, naturally. Science will assist the body to maintain nominal concentrations once the research concludes what nominal is and how nature keeps it nominal.

Posted by: Roger Duronio at May 8th, 2016 10:05 AM

Republican War on Women

The Republican's war on women is an old long policy: The great "Ronald Reagan" personally propagandized against the women's rights Constitutional Amendment while he was President and kept it from becoming the law of the land. The Republican's shoved the lying and incompetent Justice Clarence Thomas, who knowingly lied on the Senate floor about his sexual discrimination illegal actions he committed while running the executive office that heard such cases, down America's throat in 1992, George Bush's last year in office. It was a disgrace to Truth, Justice, and all of America, but especially to the Women of this nation. And now the Republicans won't do their Constitutional Duty to address Obama's Appointment to the Supreme Court.
They say women should die before having abortions and they mean it. And they have written state laws saying just that every year since the Supreme Court ruled on the Constitutionality of Abortion in 1972, making abortion totally legal. There is a War on Women and woman's legal rights and the Republicans are running it. Just like they have run the Racial discrimination policy against President Obama.

Republican revolution.

The Republican 'revolt' against being the majority party in the 10 poorest and 10 worst educated states is easily understandable. The Republican base isn't the religious, rich, and conservative: it is people hoping to get rich, have a local minister, and contact with someone who can get them a patronage job. And for the last 8 years they haven't gotten the jobs, become rich, or seen a new minister. But now, the "revolutionary' candidates have really shown what the leadership really is: lacking dignity, without respect and totally lacking in honor. Trump and Cruz have no dignity, no respect, and totally lack honor, not honorable in their views, their speech, or even their background.

Response to NYT opinionator: "Is Humanity Getting Better?"

There are several noticeable, yet overlooked, accomplishments and failings of mankind in this essay: We really are not Democracies, no citizens vote directly on the laws under which they live. Most "democracies" are republics where the people vote for Representatives who end up failing to represent the people who voted for them. Power is used selfishly, or for the 'special' interests. So actual Democracy does not exist and we must aspire to it, work for it, demand it. Who makes the rules "Rules". A second point is we know the purpose of mankind is to survive until reproduction. Consequently we should be working toward very long life spans, thousands of years, as well as freeing ourselves from the coercion of the genes to "survive until reproduction". This is simply "freedom to obey" the forces of nature, the oxytocin rewards and the vasopressin punishments of the neural-endocrine motivation pathways of our bodies. Our knowledge of physics, chemistry, biochemistry, and biology will soon give us influence over our purpose and our very form and functions. We must use this power for our benefit. The stars beckon and we will answer. Freedom beckons and we embrace it along with the political equality that will support it. We need to aspire to more than getting laid and watching our favorite sports team "win". We should influence evolution, it is too important to any longer be left to chance. We should "cure death", as Aubrey de Grey advocates; and make life "more perfect", scientifically.

Why Trump IS the best the Republican Party has.

What the 'Republican Establishment' doesn't understand is that the people in the Republican Party are sick and tired of not being represented by their Representatives. Their votes are cast and then disregarded. The two junior Senators of Cuban ancestorage are both good examples of this. They haven't done anything but aide the Senate is blocking the governing of America. They are not only not doing anything, they are keeping others from doing anything. Trump is winning because he is a better person, more truthful, more self-confident,less dependent on the Rich, who buy all the elections. Trump is the best candidate the people of the Republican Party see out there. And they are Right. Donald Trump is best Republican left, because of the void of work and effort For the People. Now they look around and say "Trump can't be the best Republican". But they are wrong, he is. And consequently, the real politicians who have worked for the Nation for the last 20 years will bury the Republicans in the general election. Not one Republican candidate can point to any accomplishment that made America better. They even failed in their prime aspiration, stopping Obama. The economy is better. More people are working. More people have health care, energy prices are down, the people feel better now than 8 ears ago: while the Republicans fought against these things happening. They now have the least competent candidate in history because he is the best the Republican party members have. Good.

reply to NYT:Can Refugees Have Human Rights?

"All men are created equal" by their "Creator": Evolution. Some of us advocate that God is a simple personification of Evolution. We know we were created by the evolution; well, at least the minimally educated know this. More importantly is the Constitution's declaration that "..no person shall be deprived of life, liberty, or property without due process of law..." It's NOT "no citizen", NOT "no taxpayer", NOT "no landowner": No person shall be deprived says all people's life , liberty, and property can only be take through the application of existing laws and only according to the protections given in the 4th, 5th, 6th, and 8th amendments. All person's include those we hate, even with reason, like Christians, Muslims, even Buddhists; or even without reason, like illegal aliens, members of opposing political parties, parents, All Representatives, ALL Torturers, All liars who got 4000 American armed service members slaughtered on foreign shores, in IRAQ, along with 25,000 wounded. because they new they could lie to America and be believed. Where are the weapons of mass destruction? In the Executive, Legislative, and Judicial branches of the American Government. American cannot survive. There is no love for the Founding Philosophy. That philosophy wasn't very great, just common sense: if you don't trust the people to vote on the laws they live under, vote for the Executives who execute the laws, vote for the judges who interpret the laws, make a REPUBLIC not DEMOCRACY.